Proceedings of the National Academy of Sciences, Volume 122, Issue 24, June 2025. SignificanceMunc13-1 is a master regulator of neurotransmitter release, which features a long low-complexity region in its N terminus. Here, we identified a functional motif in this region, termed polyE, which is unique to Munc13-1 among all Munc13 …
Observations from the Little Bunker
Last updated: August 18, 2025 04:13 PM
Atmospheric CO₂
425.4 ppm
+18.4
ppm/year
Atmospheric CH₄
1934.91 ppb
+9.11
ppb/year
Global Temperature
+1.48 °C
Peak: +1.73°C
World Population
8.1 billion
+67
million/year