Abstract This study investigates how clouds and their atmospheric radiative effects respond to meridional shifts in the Southern Hemisphere (SH) midālatitude jet, represented by the Southern Annular Mode (SAM), using reanalysis data, CloudSat/CALIPSO observations, and CMIP6 models. Consistent with previous studies, poleward jet shifts displace stormātrack clouds, creating lower tropospheric radiative heating anomalies poleward of the mean jet latitude and cooling anomalies on the equatorward side of the mean jet latitude where largeāscale subsidence increases low cloud fraction. Whether these radiative heating anomalies can affect SAM persistence is also investigated in CMIP6 models. If observed sea surface temperatures are prescribed, models that simulate low cloud responses more realistically show less SAM persistence, aligning more closely with observations. Our results based on CMIP6 models agree with a recent idealized modeling study and suggest that atmospheric cloud radiative heating anomalies, induced by the poleward jet shift, contribute to a reduction in SAM persistence.