Proceedings of the National Academy of Sciences, Volume 122, Issue 32, August 2025. SignificanceThe U.S. Food and Drug Administration recently approved the first CRISPR-Cas9 therapy, making genome editing a promising strategy for treating genetic disorders ex vivo and in vivo. Unintended or off-target genome editing increases with the …
Observations from the Little Bunker
Last updated: October 16, 2025 02:57 AM
Atmospheric CO₂
424.4 ppm
+18.2
ppm/year
Atmospheric CH₄
1933.54 ppb
+12.29
ppb/year
Global Temperature
+1.48 °C
Peak: +1.73°C
World Population
8.1 billion
+67
million/year