Proceedings of the National Academy of Sciences, Volume 122, Issue 33, August 2025. SignificanceGenetic deletion studies have revealed the diverse cellular, physiological, and pathophysiological roles of the mechanically activated PIEZO1 ion channel. However, whether these functions are directly mediated by its mechanosensitivity has …
Observations from the Little Bunker
Last updated: October 16, 2025 04:11 AM
Atmospheric CO₂
424.4 ppm
+18.2
ppm/year
Atmospheric CH₄
1933.54 ppb
+12.29
ppb/year
Global Temperature
+1.48 °C
Peak: +1.73°C
World Population
8.1 billion
+67
million/year