Proceedings of the National Academy of Sciences, Volume 122, Issue 34, August 2025. SignificanceOxygen homeostasis in complex animals requires multiple sensory mechanisms to integrate cell-autonomous actions with tissue- and system-wide feedback circuits. 2-aminoethanethiol dioxygenase (ADO)-catalyzed N-degron proteolysis is rapid, …
Observations from the Little Bunker
Last updated: October 16, 2025 02:57 AM
Atmospheric COâ‚‚
424.4 ppm
+18.2
ppm/year
Atmospheric CHâ‚„
1933.54 ppb
+12.29
ppb/year
Global Temperature
+1.48 °C
Peak: +1.73°C
World Population
8.1 billion
+67
million/year