Between June 6 and 8, 2023, wildfires in Quebec, Canada generated massive smoke plumes that traveled long distances and deteriorated air quality across the Northeastern United States (US). Surface daily PM2.5 observations exceeded 100 µg m−3, affecting major cities such as New York City and Philadelphia, while many areas lacked PM2.5 monitors, making it difficult to assess local air quality conditions. To address this gap, we developed a WRF-CMAQ-BenMAP modeling system to provide rapid, spatially continuous estimates of wildfire-attributable PM2.5 concentrations and associated health impacts, particularly benefiting regions lacking air quality monitoring. CMAQ simulations driven by two wildfire emissions datasets and two meteorological drivers showed good agreement with PM2.5 observations, with linear regression results of R2∼0.6 and slope ∼0.9. We further quantified uncertainties introduced by varying emissions and meteorological drivers and found the choice of wildfire emissions dataset alone can alter PM2.5 simulations by up to 40 µg m−3 (∼40%). Short-term health impacts were evaluated using the BenMAP model. Validation against asthma-associated emergency department (ED) visits in New York State confirmed the framework’s ability to replicate real-world outcomes, with ED visits increased up to ∼40%. The modeling results identified counties most severely affected by wildfire plumes, the majority of which lack regulatory air quality monitors. Our approach highlights the value of integrated modeling for identifying vulnerable populations and delivering timely health burden estimates, regardless of local monitoring availability.

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