Proceedings of the National Academy of Sciences, Volume 122, Issue 42, October 2025. SignificanceNonobstructive azoospermia (NOA) caused by genetic defects in meiotic genes remains untreatable, as no curative therapies exist for patients lacking male haploid germ cells. Here, we demonstrate that lipid nanoparticle (LNP)-mediated mRNA …
Observations from the Little Bunker
Last updated: November 30, 2025 04:25 AM
Atmospheric CO₂
426.8 ppm
+18.1
ppm/year
Atmospheric CH₄
1927.61 ppb
+2.73
ppb/year
Global Temperature
+1.48 °C
Peak: +1.73°C
World Population
8.1 billion
+67
million/year