Proceedings of the National Academy of Sciences, Volume 122, Issue 43, October 2025. SignificanceThis study addresses the contribution of mutant p53 to the process of cancer cell dissemination in physiologically relevant three-dimensional environments—a key characteristic of metastatic disease. Several mutant p53 proteins display pro-…
Observations from the Little Bunker
Last updated: November 30, 2025 06:15 AM
Atmospheric CO₂
426.8 ppm
+18.1
ppm/year
Atmospheric CH₄
1927.61 ppb
+2.73
ppb/year
Global Temperature
+1.48 °C
Peak: +1.73°C
World Population
8.1 billion
+67
million/year