Proceedings of the National Academy of Sciences, Volume 122, Issue 45, November 2025. SignificanceTreatments for multiple sclerosis (MS)—an inflammatory autoimmune disease—rely on systemic dosing, are noncurative, and leave patients vulnerable to infection. Here, we advance a lymph node targeting strategy that exploits local dosing and …
Observations from the Little Bunker
Last updated: November 30, 2025 04:25 AM
Atmospheric COâ‚‚
426.8 ppm
+18.1
ppm/year
Atmospheric CHâ‚„
1927.61 ppb
+2.73
ppb/year
Global Temperature
+1.48 °C
Peak: +1.73°C
World Population
8.1 billion
+67
million/year