Proceedings of the National Academy of Sciences, Volume 122, Issue 45, November 2025. SignificanceCancer cells are among the most numerous cell types that comprise the tumor microenvironment, but with respect to immune therapy, they are often underutilized. Stimulator of interferon genes (STING) agonists are a promising class of innate …
Observations from the Little Bunker
Last updated: November 30, 2025 04:25 AM
Atmospheric CO₂
426.8 ppm
+18.1
ppm/year
Atmospheric CH₄
1927.61 ppb
+2.73
ppb/year
Global Temperature
+1.48 °C
Peak: +1.73°C
World Population
8.1 billion
+67
million/year