Proceedings of the National Academy of Sciences, Volume 122, Issue 49, December 2025. SignificanceMacrophage-produced methylglyoxal can restrict the growth of bacteria likeListeria monocytogenesbut notMycobacterium tuberculosis, suggestingM. tuberculosishas mechanisms to resist methylglyoxal toxicity. Using a genetic screen, we …
Observations from the Little Bunker
Last updated: December 10, 2025 10:11 PM
Atmospheric CO₂
427.2 ppm
+17.6
ppm/year
Atmospheric CH₄
1930.95 ppb
+-3.5
ppb/year
Global Temperature
+1.48 °C
Peak: +1.73°C
World Population
8.1 billion
+67
million/year