Abstract Most studies linking atmospheric water vapor and precipitation emphasize short records, tropical regions, or the Northern Hemisphere. Longâterm variability of water vapor and its coupling with precipitation remain poorly understood across strong latitudinal and climatic gradients. Here we analyze 15â27 years of precipitable water vapor (PWV) from Global Navigation Satellite Systems (GNSS) and coâlocated rain gauges across southwestern South America. The strength of PWVâprecipitation coupling varies systematically with latitude and precipitation regime: highâelevation convective regions show strong coupling across timescales, while extratropical areas dominated by stratiform precipitation exhibit weaker annual and monthly but moderate daily relationships. Seasonal PWV ranges from âź ${\sim} $40 mm in the tropics to âź ${\sim} $6 mm in subpolar regions, yet precipitation varies inversely. Probability distributions reveal a powerâlaw PWVâprecipitation relationship only in the tropical Andes, whereas extratropical regions follow a logistic form shaped by positively skewed PWV.