Proceedings of the National Academy of Sciences, Volume 122, Issue 51, December 2025. David John “Davo” Mangelsdorf passed away on August 3, 2025, in Dallas, Texas at age 67 from an unexpected postsurgical complication. Davo made transformative contributions to nuclear receptor and metabolic biology. He discovered the retinoid X receptor (…
Observations from the Little Bunker
Last updated: December 25, 2025 02:10 PM
Atmospheric CO₂
427.2 ppm
+17.9
ppm/year
Atmospheric CH₄
1930.95 ppb
+-3.5
ppb/year
Global Temperature
+1.48 °C
Peak: +1.73°C
World Population
8.1 billion
+67
million/year