Proceedings of the National Academy of Sciences, Volume 123, Issue 4, January 2026. SignificanceLymph node metastases (LNMs) are associated with enhanced tumor aggressiveness and poor prognosis but remain therapeutically challenging due to their distinct immunosuppressive microenvironment. Surgical removal of LNMs is further complicated …
Observations from the Little Bunker
Last updated: February 24, 2026 10:22 PM
Atmospheric CO₂
429.9 ppm
+17.3
ppm/year
Atmospheric CH₄
1946.47 ppb
+6.49
ppb/year
Global Temperature
+1.48 °C
Peak: +1.73°C
World Population
8.1 billion
+67
million/year