Proceedings of the National Academy of Sciences, Volume 123, Issue 15, April 2026. SignificanceBacterial sepsis remains a major global health burden. Here, we report an essential role for the recently discovered acid-sensitive chloride channel, Proton-activated chloride channel 1 (PACC1) (PAC/ASOR/TMEM206), in protective host defense …
Last updated: April 16, 2026 01:25 AM
CO₂
431.9ppm
+1.9
/ year
CH₄
1945.85ppb
+8.44
/ year
Temp
+1.48°C
Peak +1.73°C
Population
8.1B
+67M
/ year