IntroductionColonialism, capitalism and patriarchy define the political economy of our climate crisis and environmental care. This is a regime that universalizes, defines, and dictates the multiplicity of factors that determine how nation-states, global institutions, and corporations make decisions. In the context of the climate crisis and given the inability of both governments and international agreements to address the seriousness of the situation, the time has come to build epistemic bridges between worlds. As Eduardo Viveiros de Castro argues, we have an obligation to take absolutely seriously what Indigenous peoples say. Inspired by his call, in this article we focus on other cosmoexperiences of the planet we inhabit and the co-responsibility we have towards it, to continue making human and more than human life possible.MethodsThough literature review, a case study and interviews on Indigenous ways of being in this world we reimagine how, by changing the relationality between people and nature, we can embed the praxis of environmental care in a sociability beyond the human. We engage theoretically with these lived experiences to consider how they break with the Modern utilitarian principle, how dialogues occur with political ecologies and with other anthropological positions to question the meanings of contemporary instrumental rationality and the possibilities there are for caring for our ‘big house’.ResultsAn example of ‘Big house’ Tatewarí Huahuyé, the Wixárika pilgrimage through sacred sites to Wirikuta in the state of San Luis Potosí, north central Mexico, evidences how the community practices and meanings of native peoples intermingle with their cosmoexperiences, producing care beyond the human, and how they have leveraged political and legislative resources to secure them. We situate the case of Tatewarí Huahujé within the wider context of cosmopolitical acts in Mexico during the preceding decades.DiscussionCosmoexperiences and the defense of territories can promote new relationships between people and the environment at a larger scale. The Casa Grande is both a cosmoexperience and the possibility for living together and caring for our diverse planet and its people.