Abstract From 2020 to 2023, prolonged droughts affected Central‐West Asia, East Africa, and North America, causing widespread disruptions to regional hydroclimate and ecosystems. These droughts coincided with an unusually persistent cold state of the tropical Pacific associated with consecutive La Niña events. Here we demonstrate a robust historical linkage between consecutive La Niña events and pan‐regional prolonged droughts across these regions. We show that the sustained cooling of tropical Pacific sea surface temperatures maintains large‐scale atmospheric circulation anomalies that suppress moisture transport and precipitation, leading to persistent regional water deficits. Land–atmosphere feedbacks further amplify drought persistence in East Africa, while suppressing drought conditions in the other regions. In addition, observations indicate that the increasing frequency of consecutive La Niña events in recent decades coincides with a rise in prolonged drought occurrence across these regions. These results highlight the tropical Pacific as a key oceanic source of predictability for pan‐regional drought variability.